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The crash between a tour bus and a tractor trailer has also shut down I-40 in both directions, east of Knoxville.

The director of national intelligence says that with 70 percent of spy agency staff on furlough, essential staff are being stretched thin.

The Clinical Center at the National Institutes of Health in Maryland is often the last resort for patients who have mysterious, rare or terminal diseases. Patients sometimes call it the "House of Hope." But the government shutdown may mean that prospective patients will be turned away.

Intelligence chiefs said recent media reports are wrong about their efforts to gather information about the social networks of Americans. They told a Senate panel such efforts are focused on foreigners. But NSA chief Keith Alexander admitted the agency has collected cellphone location information, as part of a short-lived test program years ago.

Payment of veterans' benefits is one of the most emotionally charged issues affected by the shutdown. Politicians of both parties have scrambled to show their support for vets. While the most serious consequences won't come unless the shutdown lasts for weeks, veterans applying for new benefits may already be suffering because of a backlog of claims.

After 16 years at Louis Vuitton, Mark Jacobs is expected to focus on an eventual IPO for his own brand, which could come within three years. Investors are interested, partly because the designer Michael Kors had a public offering in 2011, and since then shares have tripled in value.

A ship packed with African migrants trying to reach Italy apparently caught fire before sinking. It's thought there were about 500 people on board. The vessel had set off from Libya, authorities say.

Richard Rodriguez's autobiographical essay collection, Darling, chronicles a complex personal history and attempts to reconcile the author's sexual, religious and cultural identities. Reviewer Cord Jefferson calls it an "eccentric mélange" — a true salvation while wandering the literary desert.

The famed hall's five full-time stagehands went on strike, and that forced the cancellation of one gala. Tax records show their average total compensation is more than $400,000 each a year. The dispute was over whether they'll also be working in the hall's new Education Wing.

The Labor Department says it won't be releasing its closely watched monthly jobs figures as scheduled on Friday due to the government shutdown. That will leave Federal Reserve policymakers, economists and financial markets without key data for making decisions.