Eli Lilly & Co. is ending a clinical trial of its antibody drug in hospitalized COVID-19 patients after federal researchers concluded the therapy doesn't work on them.

An Orange County brush fire that ignited Monday morning has left two firefighters critically injured, ravaging more than 4,000 acres and forcing the evacuation of about 60,000 residents.

Strong winds gusts up to 70 mph moving up and down California fed the flames of the Silverado Fire in Irvine, which erupted in the Santa Ana Mountains around 6:45 a.m. local time.

Weekend snowfall granted a reprieve against the two largest wildfires in Colorado history, which together have spread over more than 400,000 acres.

But the fires continue to burn. The East Troublesome Fire spread 192,560 acres and jumped the Continental Divide. It is 15% contained.

The nearby Cameron Peak Fire, the largest blaze in state history, is now 64% contained. It has already burned over 208,600 acres.

With about a week still remaining until Election Day, Americans have already cast a record-breaking 62 million early ballots, putting the 2020 election on track for historic levels of voter turnout.

That's some 15 million more pre-election votes than were cast in the 2016 election, according to the U.S. Elections Project, a turnout-tracking database run by University of Florida professor Michael McDonald.

Colorado is among the states experiencing a surge in COVID-19 cases. In August, the state logged about 2,000 new cases a week. Last week, that number jumped to more than 8,000.

The state's Democratic governor, Jared Polis, warns that the situation could worsen in the coming months.

Zeta has officially strengthened into a hurricane, and is predicted to make landfall late Monday on Mexico's Yucatan Peninsula before setting its sights on the U.S.

It started as a ripple: anger over higher subway prices. But a growing wave of protests followed, and now people in Chile have voted overwhelmingly to throw out their country's Pinochet-era constitution and create a new document under which to live. Nearly 80% of the voters chose to form a new constitution.

The result threw Chile into a huge celebration. One year after Santiago's streets were jammed by protesters, they were filled Sunday with revelers, ecstatic over the results of a national plebiscite. There were music and fireworks. Signs declared "Renace Chile" — Chile Reborn.

Editor's note: This story includes details some readers may find disturbing.

An unprecedented trial is underway this month at the Vatican, the result of a whistleblower going public.

A young priest is charged with sexually abusing an altar boy over a five-year period inside Vatican City walls. An older priest is charged with covering up the abuse.

It's the first criminal trial for sexual abuse to take place in the Vatican court.

To make ends meet, Martha Tapia works 64 hours a week at two Orange County, Calif., nursing homes. She is one of thousands of certified nursing assistants who perform the intimate and physical work of bathing, dressing and feeding the nation's fragile elderly.

"We do everything for them. Everything you do for yourself, you have to do for the residents," Tapia says.

One week after Virginia Gov. Ralph Northam opened an investigation into systemic racism at the Virginia Military Institute, the college's superintendent has submitted his resignation.