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President Bush announces the resignation of Defense Secretary Donald Rumsfeld at a White House news conference. In a later media session, Bush and Rumsfeld shared a podium with Rumsfeld's successor, former CIA chief Robert Gates. Melissa Block talks with NPR's John Hendren.

Each week, guests and hosts on NPR's Pop Culture Happy Hour share what's bringing them joy. This week: the Mystery Menu series, The Alarmist podcast, Every Body and Two Can Play That Game.

In a classified memo to President Bush, National Security Council officials expressed doubts about the ability of Iraqi Prime Minister Nouri al-Maliki to control violence in his country. The memo notes that al-Maliki relies on extreme Shiite groups for support. Mike Pesca speaks with Michael Gordon, the New York Times reporter who broke the story.

The Supreme Court rejects two Bush administration plans — one on global warming, the other on coal-fired power plants. The decisions are the latest in a string of setbacks the administration has suffered in the courts.

Condemnation from the United States and other nations may be just what the Iranian president needs to shore up a shaky political position at home.

The 2007 Nobel Prize in physics will be shared by two Europeans who discovered the physics that allows computer hard drives to compress large amounts of data. The prize was awarded to Albert Fert of France and Peter Grunberg of Germany.

Karl Rove, President Bush's closest political adviser, is a longtime member of Bush's inner circle. He was nicknamed "the architect" by the president for designing the strategy that twice captured the White House.

Israel Wednesday again closed the border crossings into the Gaza Strip in retaliation for rocket attacks from Gaza into the southern city of Sderot. Hamas called the move a violation of a truce, but urged Palestinian factions to hold their fire.

The Family Leader Summit in Des Moines is a gathering of evangelical Christians in a state where they have immense political power. Republican presidential candidates should be there.

Concerned that questions about his Mormon faith are hurting his presidential campaign, Mitt Romney will give a speech on "Faith in America" on Thursday. The situation recalls that faced by John F. Kennedy in 1960, when he gave a historic speech two months before he was elected the first Catholic president.